Our genome is made up of 20,000 genes, all of which may cause disease. At present, 4,141 genes have been identified as being responsible for genetic abnormalities, leaving around 16,000 genes with unknown implication in disease. Researchers from the University of Geneva (UNIGE), Switzerland, — working in collaboration with scientists from Pakistan and the USA — have investigated a recessive genetic disorder that destroys the eyes from developing and results in childhood blindness. After analyzing the genomes of each member of a consanguineous family with affected children, the geneticists pinpointed pathogenic mutations in a new gene, MARK3, as being the cause. They subsequently confirmed their findings — published in the journal Human Molecular Genetics — by modifying the homologous gene in drosophila flies, which resulted in abnormal eye development and blindness. The identification of the MARK3 related disease will help to understand the mechanism of the disease, provide diagnostic services, and initiate efforts for a personalized treatment. (1)
The same genes which are praised for
their role in life…
Are responsible for the diseases which
destroy it…
Could it be that these genes work the
wrong way?
Or that we are seeing the whole
picture from a wrong standpoint?
Can what is good be evil at the same
time?
Can health entail disease?
Can life entail death?
What an irrational cosmos…
So alive. So sad. So true…
Look at the circle on the sand.
The line is blurry.
Distracted by the wind.
Please don’t touch my circle…
Blood on the sand.
A cry of a bird in the distance.
The deep ocean cries…
The Polar Star stands still.
