Deadly life…

Advertisements
Photo by Leo Cardelli from Pexels

A once-maligned genetic parasite may actually be essential for survival.

Mouse embryos need that genetic freeloader — a type of jumping gene causing mutations, or transposon, called LINE-1 — to continue developing past the two-cell stage, researchers reported in Cell.

Transposons certainly can hop into and break genes, and cells deploy numerous tools to prevent the jumping genes from making RNA and protein copies of themselves. But, in early development, LINE-1 is turned on nearly full blast, packing RNA into embryonic cells as well as “germline” cells, which later give rise to eggs and sperm.

To see what the jumping gene was doing in the cells, scientists used a short piece of RNA that could pair up with LINE-1 RNA and cause the transposon to be degraded, essentially turning off the jumping gene. (The researchers couldn’t simply remove LINE-1 from a cell; there are thousands of copies) Without LINE-1 RNA, embryonic stem cells stopped making more of themselves and mouse embryos failed to progress past the two-cell stage of development. (1)

Meet life.

In death.

Look into the ground you step upon.

For mother Earth, life and death were never important.

Live. Die. Be.

This is the essence of life.

Author: skakos

Spiros Kakos (or Spyros Kakos or Spyridon Kakos) [Σπύρος Κάκος] is a thinker located in Athens, Greece. He has been the Chief Editor of Harmonia Philosophica since its inception. Spiros has a diploma in Chemical Engineering, an MSc in Advanced Materials' Technology, an MBA in Decisions' Science, a phD in the use of conductive polymers in PCB industry and is still learning. He also worked as a technical advisor and a researcher in the Advanced Materials sector for many years in the past. In his free time he develops software solutions and contributes to the open source community. He is the creator of Huo Chess, one of the smallest micro-chess programs ever that is perfect for educational purposes. He believes that science and religion are two sides of the same coin and is profoundly interested in Religion and Science philosophy, as well as the philosophy of the irrational. His philosophical work is mainly concentrated on an effort to free thinking of "logic" and reconcile all philosophical opinions under the umbrella of the "One" that Parmenides - one of the first thinkers - visualized. Since our thought is dictated by our assumptions, the only way to free it and know cosmos as it is, is to think irrationally and destroy everything we have built. The "Harmonia Philosophica" articles program is the tool that will accomplish that. Life's purpose is to be defeated by greater things. And the most important things in life are illogical. We must fight the dogmatic belief in "logic" if we are to stay humans. We should stop thinking in order to think. Credo quia absurdum!

Exit mobile version
%%footer%%