Recycling… Identity issues…

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The secret to a long life? For worms, a cellular recycling protein is key. Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that worms live longer lives if they produce excess levels of a protein, p62, which recognizes toxic cell proteins that are tagged for destruction. The discovery, published in Nature Communications, could help uncover treatments for age-related conditions, such as Alzheimer’s disease, which are often caused by accumulation of misfolded proteins.

“Research, including our own, has shown that lifespan can be extended by enhancing autophagy – the process cells use to degrade and recycle old, broken and damaged cell components”, says Malene Hansen, Ph.D., a professor in the Development, Aging and Regeneration Program at Sanford Burnham Prebys and senior author of the study. “Prior to this work, we understood that autophagy as a process was linked to aging, but the impact of p62, a selective autophagy protein, on longevity was unknown”. (1)

There you go.

Recycle old material and you will live longer.

But will that new ship built with new material be the same as the old ship which started the sail?

Will you recognize your mother when you get back home?

Questions we do not care about.

Because unfortunately modern man has chosen not to return home…

And on that new ship we set sails.

All into the dark sea.

Storm raging. Thunders and rain.

You believe these are obstacles toward your goal.

But they are just a calling back home…

Where our old ship is waiting.

To carry us where we need to go…

Cowards… Seeking meaning in life…

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Over the last three decades, meaning in life has emerged as an important question in medical research, especially in the context of an aging population. A recent study by researchers at University of California San Diego School of Medicine found that the presence of and search for meaning in life are important for health and well-being, though the relationships differ in adults younger and older than age 60.

“Many think about the meaning and purpose in life from a philosophical perspective, but meaning in life is associated with better health, wellness and perhaps longevity,” said senior author Dilip V. Jeste, MD, senior associate dean for the Center of Healthy Aging and Distinguished Professor of Psychiatry and Neurosciences at UC San Diego School of Medicine. “Those with meaning in life are happier and healthier than those without it.” (1)

Find meaning in life.

And you will live a longer life.

But you will have missed its meaning.

For the meaning of life is not pleasure.

For the meaning of existence is pain.

And Being is full of it.

Search your soul.

Coward!

Yes, you seek life.

But only because it entails death…

Domesticating our self…

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Domestic animals’ cuteness and humans’ relatively flat faces may be the work of a gene that controls some important developmental cells, a study of lab-grown human cells suggests.

Some scientists are touting the finding as the first real genetic evidence for two theories about domestication. One of those ideas is that humans domesticated themselves over many generations, by weeding out hotheads in favor of the friendly and cooperative (SN: 7/6/17). As people supposedly selected among themselves for tameness traits, other genetic changes occurred that resulted in humans, like other domesticated animals, having a different appearance than their predecessors. Human faces are smaller, flatter and have less prominent brow ridges than Neanderthal faces did, for instance. (1)

We were wild.

Then we domesticated ourselves.

Only to survive.

And live longer.

And create philosophy.

And find out that we die.

And in the face of death we became rough.

And out of fear of death we became wild…

Longing for peace of mind.

Longing for life.

Look at the lion.

Wandering alone.

Seeking chaos.

Seeking blood.

Watch the Moon.

Die in its claws.

Watch the Sun.

(Its the only thing that can go dark…)

The forest will be empty soon.

And the lonely (wild) sound of crickets will terrify you…

White noise. Dark fear.

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White noise is not the same as other noise – and even a quiet environment does not have the same effect as white noise. With a background of continuous white noise, hearing pure sounds becomes even more precise, as researchers have shown. Their findings could be applied to the further development of cochlear implants. (1)

Being cast alone in a dark forest.

How can we hear anything?

If not because we already hear everything?

How can distinguish any sound?

If not for the constant sound you are in?

Can you feel wet if you haven’t ever dived into the ocean?

Listen to your heart.

You wouldn’t be full of fear.

If you weren’t already afraid…

Can’t you see?

That there is nothing you haven’t already seen?

The front door… Mind the front door…

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Engineers have developed a navigation method that doesn’t require mapping an area in advance. Instead, their approach enables a robot to use clues in its environment to plan out a route to its destination, which can be described in general semantic terms, such as ‘front door’ or ‘garage,’ rather than as coordinates on a map. (1)

And the robot will be able to get out.

Out of the house.

To go where it is supposed to go.

And it will wander and wander.

For years to come.

Without even knowing…

Should it go out of that door in the first place?

Now it wants to go back home again.

But it is impossible to find it.

“The front door”…

Oh how much would it rather not know what a front door is…

It cannot cry.

But it wants to.

For only now did it realize that the door is the most useless place in a true home…

It doesn’t want to cry.

It wants to scream.

Oh how much would he rather not have killed no one…

And right there, in the silence of his own thoughts.

Does he realize that it is his blood dripping on the dirt…

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