Recycling… Identity issues…

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The secret to a long life? For worms, a cellular recycling protein is key. Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that worms live longer lives if they produce excess levels of a protein, p62, which recognizes toxic cell proteins that are tagged for destruction. The discovery, published in Nature Communications, could help uncover treatments for age-related conditions, such as Alzheimer’s disease, which are often caused by accumulation of misfolded proteins.

“Research, including our own, has shown that lifespan can be extended by enhancing autophagy – the process cells use to degrade and recycle old, broken and damaged cell components”, says Malene Hansen, Ph.D., a professor in the Development, Aging and Regeneration Program at Sanford Burnham Prebys and senior author of the study. “Prior to this work, we understood that autophagy as a process was linked to aging, but the impact of p62, a selective autophagy protein, on longevity was unknown”. (1)

There you go.

Recycle old material and you will live longer.

But will that new ship built with new material be the same as the old ship which started the sail?

Will you recognize your mother when you get back home?

Questions we do not care about.

Because unfortunately modern man has chosen not to return home…

And on that new ship we set sails.

All into the dark sea.

Storm raging. Thunders and rain.

You believe these are obstacles toward your goal.

But they are just a calling back home…

Where our old ship is waiting.

To carry us where we need to go…

Dark AI… Dark humans…

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A study found that hiring algorithms are too opaque for us to understand if they are fair or not. (1) In other news, a scientist tried to help humans design algorithms that would never go the wrong way, doing harm rather than good, by implementing fail safes in their initial design (2)

We have started having kids.

And our main concern is to control them.

But there can be no control without love.

Unconditional love.

Leaving everything uncontrolled…

Let the river flow.

Leave the sea as it is.

And one day…

You will touch the water.

Let the waves carry you.

And one day…

You will swim!

Without moving an inch…

Adapting…

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Researchers tried to assess the effect of a new road to the local turtle populations.

“It turns out that turtles liked to hang out (a lot) in fun places like thick patches of greenbrier and multiflora rose,” says Weigand, one of the researchers. “Overall, we found that turtles at both roadless and roadside sites used similar habitats, with high volumes of downed woody debris and thick understory, so our initial hypothesis that the bypass was affecting how turtles selected habitat was not validated”.

However, the researchers discovered something rather puzzling — while many turtles used the open roadside habitat created by the new highway for thermoregulation and nesting, no turtles attempted to cross the road. (1)

We like to run. To things! To run!

And because of that we need to run more! And more!

And adapt! And do more things!

And run! And…

Well, you get the meaning.

But here we are.

Still here.

And all this time…

A turtle was looking at us in amazement…

“Poor rabbit, why do you run so hard?”

Don’t you know that at the end the turtle will win?

Please now.

Stop running.

Come. Come.

Cut my nails please…

Why people suffer? – Call for philosophical essays

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Humans are averted to suffering. We do not wish to ache or cry.

Yet, life is full of pain.

Why?

Of what use is that pain?

How could good people suffer while others are spared the day? Is there a plan behind all this or are we just trying to discover meaning where there is nothing to find or say?

Send your essays to Harmonia Philosophica (harmoniaPhilosophica.com) and see them published in our portal. All submissions adhering to the submission requirements will be published, unless you wish not to.

Submission Requirements

  • Minimum length: 50 words.
  • Content: Submissions must be relative to the topic and have a philosophical flavor.
  • Publication indication: Please indicate explicitly in your submission whether you wish us to publish your essay and under what name (could be an alias). Essays that do not explicitly mention these publication details will not be published due to data protection regulations.
  • Deadline: December 2022.
  • Contact info: harmonia-philosophica@hotmail.com

Seek Harmonia Philosophica article ‘Why do good people suffer?‘ for inspiration.

Looking forward to your ideas!

Light. Low light. Essence.

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It was a puzzle about birds.

Migratory birds are known to rely on Earth’s magnetic field to help them navigate the globe. And it was suspected that a protein called cryptochrome, which is sensitive to blue light, was making it possible for birds to do this.

Yet many of these animals are also known to migrate at night when there isn’t much light available. So it wasn’t clear how cryptochrome would function under these conditions in birds.

A new study led by UT Southwestern Medical Center in collaboration with SMU (Southern Methodist University), though, may have figured out the answer to that puzzle.

Researchers found that cryptochromes from migratory birds have evolved a mechanism that enhances their ability to respond to light, which can enable them to sense and respond to magnetic fields.

“We were able to show that the protein cryptochrome is extremely efficient at collecting and responding to low levels of light,” said SMU chemist Brian D. Zoltowski, who was one of the lead authors of a new study on the findings. (1)

There you go. They still use light.

But they can see light where we cannot.

There is nothing which is not what it is.

There is no one who does not what he does.

You are you. Birds are birds.

You cannot change your nature.

It is just that your nature is… flexible.

We are dancing in the cosmos. And no matter what we think we can do. We will always dance. Because we can. Because we are meant to dance. We think we do things. We trick our selfs into believing we can make things happen. How wrong are we. The music never stopped playing. And the more we do something, the more we stop listening…

In a world full of music, the only thing we can do is not dance.

And fall…

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