The secret to a long life? For worms, a cellular recycling protein is key. Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that worms live longer lives if they produce excess levels of a protein, p62, which recognizes toxic cell proteins that are tagged for destruction. The discovery, published in Nature Communications, could help uncover treatments for age-related conditions, such as Alzheimer’s disease, which are often caused by accumulation of misfolded proteins.
“Research, including our own, has shown that lifespan can be extended by enhancing autophagy – the process cells use to degrade and recycle old, broken and damaged cell components”, says Malene Hansen, Ph.D., a professor in the Development, Aging and Regeneration Program at Sanford Burnham Prebys and senior author of the study. “Prior to this work, we understood that autophagy as a process was linked to aging, but the impact of p62, a selective autophagy protein, on longevity was unknown”. (1)
There you go.
Recycle old material and you will live longer.
But will that new ship built with new material be the same as the old ship which started the sail?
Will you recognize your mother when you get back home?
Questions we do not care about.
Because unfortunately modern man has chosen not to return home…
And on that new ship we set sails.
All into the dark sea.
Storm raging. Thunders and rain.
You believe these are obstacles toward your goal.
But they are just a calling back home…
Where our old ship is waiting.
To carry us where we need to go…